Ocular inflammatory manifestations induced by dengue virus infection

Authors

  • Marcelo Rudzinski Catedra de Oftalmología, Universidad Católica de las Misiones, Posadas, Misiones, Argentina.
  • Adriana E. Echeverría Hospital de agudos Ramón Madariaga, Parque de la Salud, Posadas, Misiones, Argentina.

DOI:

https://doi.org/10.70313/2718.7446.v13.n3.23

Keywords:

dengue, ocular manifestations, 2020 epidemic

Abstract

Dengue infection can produce a wide clinical spectrum of inflammatory manifestations in the eye. Ocular manifestations during the critical period of the disease are more frequently associated with vascular damage induced by the viral protein NS1. Sight-threatening retinal conditions in that period include posterior uveitis and dengue maculopathy. Retinal hemorrhages, edema, vasculitis and exudative retinal detachment are the most frequent presentations of posterior uveitis. SD-OCT and OCTA are tools capable to locate the affected retinal layers and capillary plexus involved in the retinopathy. Neuroophthalmological manifestations although infrequent are an important cause of visual disturbance, inducing ophthalmological inter-consults in hospitalized patients. Available treatments include supportive measures, systemic corticosteroids and intravenous immunoglobulin. There is an urgent need for clinical studies to test drugs known to restore vascular permeability as well as new antiviral drug candidates.

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Published

2020-09-18

Issue

Section

Review Articles

How to Cite

1.
Rudzinski M, Echeverría AE. Ocular inflammatory manifestations induced by dengue virus infection. Oftalmol. clín. exp. 2020;13(3). doi:10.70313/2718.7446.v13.n3.23

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