Retrospective study of keratoplasties performed in a public hospital in Montevideo, Uruguay
DOI:
https://doi.org/10.70313/2718.7446.v16.n01.209Keywords:
corneal transplantation, epidemiology, keratoconus, infectious keratitis, UruguayAbstract
Objective: To describe the characteristics of corneal transplants performed in a public hospital in the city of Montevideo, Uruguay.
Methods: A retrospective study was designed where the cases of patients with corneal transplantation performed at the Hospital de Clínicas Dr. Manuel Quintela in Montevideo (Uruguay) between July 2018 and May 2022 were reviewed In each case, the indications for surgery, the waiting time for keratoplasty from the time of the diagnosis and the type of technique performed.
Results: We found 56 penetrating keratoplasties performed. The mean age of the patients was 58 ± 19.63 years (15-83) where 61% were male. In relation to the reason, 29 cases (51.8%) were performed with an optical purpose and 27 (48.2%) with a therapeutic/tectonic purpose as an emergencies. In relation to etiology of keratoplasties with optic purpose, 37.9% were due to keratoconus, 27.6% due to herpetic keratitis, 10.3% post-microbial (excluding viral), pseudophakic bullous keratopathy in 6.9%, retransplantation 6.9% and due to corneal leukoma of uncertain etiology 6.9%. The 43.9% were patients from Montevideo and 56.1% from other parts of Uruguay. For transplants with optical purposes, the mean waiting time for surgery was 26.6 ± 13.78 months (6-55).
Conclusion: Of all the procedures, almost half were tectonic, mainly caused by infections. The waiting time for procedures with an optical purpose was slightly more than 2 years.
Downloads
References
Pascolini D, Mariotti SP. Global estimates of visual impairment: 2010. Br J Ophthalmol 2012; 96: 614-618.
Foster A, Gilbert C, Johnson G. Changing patterns in global blindness: 1988-2008. Community Eye Health 2008; 21: 37-39.
Ple-Plakon PA, Shtein RM. Trends in corneal transplantation: indications and techniques. Curr Opin Ophthalmol 2014; 25: 300-305.
Niederkorn JY, Stein-Streilein J. History and physiology of immune privilege. Ocul Immunol Inflamm 2010; 18: 19-23.
Zirm E. Eine erfolgreiche totale Keratoplastik. Albrecht von Graefes Archiv für Ophthalmologie 1906; 64: 580-593.
Melles GR, Eggink FA, Lander F et al. A surgical technique for posterior lamellar keratoplasty. Cornea 1998; 17: 618-626.
Melles GRJ, Wijdh RH, Nieuwendaal CP. A technique to excise the descemet membrane from a recipient cornea (descemetorhexis). Cornea 2004; 23: 286-288.
Melles GRJ, Ong TS, Ververs B, van der Wees J. Descemet membrane endothelial keratoplasty (DMEK). Cornea 2006; 25: 987-990.
Terry MA, Ousley PJ. Deep lamellar endothelial keratoplasty in the first United States patients: early clinical results. Cornea 2001; 20: 239-243.
Anwar M, Teichmann KD. Big-bubble technique to bare Descemet’s membrane in anterior lamellar keratoplasty. J Cataract Refract Surg 2002; 28: 398-403.
Soong HK, Malta JB. Femtosecond lasers in ophthalmology. Am J Ophthalmol 2009; 147: 189-197.
Park CY, Lee JK, Gore PK et al. Keratoplasty in the Unites States: a 10-year review from 2005 through 2014. Ophthalmology 2015; 122: 2432-2442.
Eye Bank Association of America (EBAA). 2016 Eye banking statistical report. Washington, DC: EBAA, 2017.
Yalniz-Akkaya Z, Burcu A, Doğan E et al. Therapeutic penetrating keratoplasty for infectious and non-infectious corneal ulcers. Int Ophthalmol 2015; 35: 193-200.
Alvarez I, Bengochea M, Mizraji R et al. Three decades of the history of donation and transplantation in Uruguay. Transplant Proc 2009; 41: 3495-3499.
Uruguay. Ley 18.968. Donación y trasplante de células, órganos y tejidos. Normativa del INDT, modificación de la ley Nº 14.005. Publicada en 21/09/2012. Disponible en: www.indt.edu.uy.
International Registry in Organ Donation and Transplantation. Database: Uruguay. Disponible en: https://www.irodat.org/?p=database&c=UY&year=2020#data.
Godino M, Machín D, Saldías MC, Mizraji R, Castro A, Bengochea M. PRO-VER. ¿Puede el Hospital de Clínicas transformarse en un hospital de referencia nacional para la procuración de córneas? Presentación del proyecto PROVER para la obtención de córneas. Semana académica 2021 Hospital de Clínicas. Disponible en: https://www.semanacademica.hc.edu.uy/index.php/galeria-eposters-2021/284-puede-el-hospital-de-clinicas-transformarse-en-un-hospital-de-referencia-nacional-para-la-procuracion-de-corneas-presentacion-del-proyecto-pro-ver-para-optimizar-la-obtencion-de-corneas
Wang JY, Xie LX, Song XS, Zhao J. Trends in the indications for penetrating keratoplasty in Shandong, 2005-2010. Int J Ophthalmol 2011; 4: 492-497.
Gain P. Jullienne R. He Z et al. Global survey of corneal transplantation and eye banking. JAMA Ophthalmol 2016; 134: 167-173.
Mora M, Cortés MC, Plata MC, Suárez Acosta D. Corneal transplant epidemiology in a reference center in Bogotá, Colombia (2010-2017). Pan-Amer J Ophthalmol 2021; 3. 39-49.
Kramer L. Corneal transplant wait list varies across Canada. CMAJ 2013; 185: E511-E512.
Almeida HG, Souza ACD. Epidemiological profile of patients waiting for penetrating keratoplasty in state of Pernambuco, Brazil. Rev Bras Oftalmol 2014; 73: 28-32.
Almeida HG, Hida RY, Kara-Junior N. Trends in corneal transplantation from 2001 to 2016 in Brazil. Arq Bras Oftalmol 2018; 81: 529-538.
Freitas LSM, Rocon PC, de Almeida AV et al. Corneal donor profile and evolution of corneal donation in a Brazilian state where the number of individuals on the waiting list reached zero but increased again. Transplant Proc 2018; 50: 509-512.
Ballouz D, Sawant OB, Hurlbert S et al. Impact of the COVID-19 pandemic on keratoplasty and corneal eye banking. Cornea 2021; 40: 1018-1023.
Downloads
Published
Issue
Section
License
Copyright (c) 2023 Consejo Argentino de Oftalmología
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Con esta licencia no se permite un uso comercial de la obra original, ni la generación de obras derivadas. Las licencias Creative Commons permiten a los autores compartir y liberar sus obras en forma legal y segura.
