Efecto de la variación postural en la profundidad de la cámara anterior y la presión intraocular en pacientes con glaucoma pseudoexfoliativo versus glaucoma primario de ángulo abierto

Javier F. Casiraghi; Juan Manuel Rodriguez; Agustina Meola

doi:10.70313/2718.7446.v17.n03.347

Authors

Javier F. Casiraghi Sección de Glaucoma, Cátedra de Oftalmología, Hospital de Clínicas “José de San Martín”, Universidad de Buenos Aires, Buenos Aires, Argentina
Juan Manuel Rodriguez Servicio de Oftalmología, Hospital Privado de Comunidad, Mar del Plata, Buenos Aires, Argentina
Agustina Meola Sección de Glaucoma, Cátedra de Oftalmología, Hospital de Clínicas “José de San Martín”, Universidad de Buenos Aires, Buenos Aires, Argentina

DOI:

https://doi.org/10.70313/2718.7446.v17.n03.347

Keywords:

pseudoexfoliative syndrome, intraocular pressure postural variation, anterior chamber postural variation, postural changes

Abstract

Objective: To determine the differences between eyes with pseudoexfoliative glaucoma (PEG) and others with primary open angle glaucoma (POAG), in sitting vs. supine position.
Methods: A single-center prospective comparative study was performed from April 2021 to May 2022. Patients with GPX (group 1) and GPAA (group 2) were selected.
Variables were compared between both, in different corportal position: anterior chamber depth (ACD) and intraocular pressure (IOP).
Results: Thirty-four eyes of 17 patients were included. The average ACD value in the sitting position was 2.76 ± 0.36 mm (group 1) and 2.32 ± 0.15 mm (group 2). The average ACD increased from 2.76 ± 0.36 mm to 3.04 ± 0.34 mm in GPX eyes and from 2.32 ± 0.15 mm to 2.39 ± 0.17 mm in GPAA eyes with postural change from sitting to supine position. ACD increased in both groups of eyes in the supine position, being more significant in group 1 (p <0.0001 in group 1, p = 0.001 in group 2). IOP in the sitting position was 17.05 ± 2.58 mmHg (group 1) and 14.78 ± 3.53 mmHg (group 2).
The difference in IOP between the sitting and supine positions increased statistically significantly in group 1 but not in group 2 (p=0.0019, p=0.62, respectively).
Conclusions: There was a greater increase in IOP in GPX patients from sitting to supine position than in GPAA patients and a significant increase in anterior chamber depth in the pseudoexfoliation group.

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