Resultados visuales, refractivos y estructurales a largo plazo en bebés prematuros tratados por retinopatía del prematuro

Priscila M. Viotto; Erna G. Knoll; Evangelina Esposito; Alejandro Gonzalez-Castellanos; Agustina  Ibañez; Julio A. Urrets-Zavalia

doi:10.70313/2718.7446.v17.n03.343

Authors

Priscila M. Viotto Department of Ophthalmology University Clinic Reina Fabiola Universidad Católica de Córdoba, Argentina
Erna G. Knoll Departamento de Oftalmología, Clínica Universitaria Reina Fabiola, Universidad Católica de Córdoba, Argentina. ; Departamento de Oftalmología, Hospital Maternal y Neonatal Ramón Carrillo, Córdoba, Argentina.
Evangelina Esposito Departamento de Oftalmología, Clínica Universitaria Reina Fabiola, Universidad Católica de Córdoba, Argentina.
Alejandro Gonzalez-Castellanos Departamento de Oftalmología, Clínica Universitaria Reina Fabiola, Universidad Católica de Córdoba, Argentina.
Agustina Ibañez Departamento de Oftalmología, Clínica Universitaria Reina Fabiola, Universidad Católica de Córdoba, Argentina.
Julio A. Urrets-Zavalia

DOI:

https://doi.org/10.70313/2718.7446.v17.n03.343

Keywords:

retinopathy of prematurity, laser photocoagulation, antiangiogenic intravitreal injection, myopia

Abstract

Purpose: To analyze the best-corrected visual acuity, refractive state and anatomical long-term results in premature infants consecutively treated for ROP by laser photocoagulation and/or intravitreal injections of anti-angiogenic agents.
Methods: Retrospective analytical study. Those children treated for ROP since 1998 by laser photocoagulation, intravitreal injections of antiangiogenic agents, or both, and who had a minimum ophthalmological follow-up of three years post-treatment were included. Descriptive and frequency statistics were used, and the Chi-square test and Spearman’s correlation test were used for statistical association.
Results: 123 eyes of 62 patients were studied. The age at the last control was on average 9.66± 5.61 years. 116 eyes (94%) were treated by laser photocoagulation, 5 (4%) eyes required combined treatment, and 2 (2%) eyes with intravitreal injection of antiangiogenics. The mean spherical equivalent was -2.68±4.87 diopters, being significantly more negative in those with combined treatment (-11.54±2.36 D) and re-treatment (-12.46±3.26 D) and in those with posterior area disease (-7.50±5.49 vs +0.52±0.54 D) (p<0.01). Sixteen (15%) eyes were emmetropic, 32 (29%) eyes were hyperopic, and 62 (57%) eyes were myopic. 82 (74%) eyes had astigmatism and 20 (37%) patients had anisometropia. Sixty (60%) eyes had good visual acuity, 26 (25%) eyes had regular visual acuity and 16 (15%) had poor visual acuity. In 97 (80%) eyes the fundus did not present sequelae of the disease or other pathologies.
Conclusions: Most treated children retain good visual acuity, despite significant refractive errors, mainly myopia. The more posterior the disease, the higher the prevalence of high myopia.

Author Biography

Erna G. Knoll, Departamento de Oftalmología, Clínica Universitaria Reina Fabiola, Universidad Católica de Córdoba, Argentina. ; Departamento de Oftalmología, Hospital Maternal y Neonatal Ramón Carrillo, Córdoba, Argentina.

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