Ocular neuromyotonia post radiotherapy

case report

Authors

  • Roberto Ebner Unidad de Neurooftalmología, Servicio de Oftalmología, Hospital Británico de Buenos Aires

DOI:

https://doi.org/10.70313/2718.7446.v16.n03.244

Keywords:

diplopia, myotonia, radiation, ephaptic transmission

Abstract

Objective: A case of ocular myotonia three decades after surgery of the selar region followed by radiotherapy is presented.

Clinical case: A 52-year-old female patient reported inconstant diplopia appearing a few years before the consultation. Although she presented residual paresis of the right third cranial nerve post-operatively, the diplopia she refers is new and does not behave like those caused by neuro-muscular plate involvement or by a new selar mass or other associated pathologies. The study of specific neuroimaging for cranial nerves allowed to demonstrate the presence of edema of the third affected nerve.  Treatment with membrane stabilizers and application of botulinum toxin in the middle rectus of the right side of the right side of the right eye was established to provide a solution to this type of diplopia.

Conclusion: Neuromyotonia is an infrequent situation in patients irradiated after surgery of the selar region. Early or late onset of inconstant diplopia leads to the diagnosis of NMO, after ruling out myasthenia, presence of new selar mass and others, by neuro-ophthalmologic evaluation and appropriate imaging.

References

JohnLeigh and David Zee. The Neurology of Ocular Movements 2nd ed. Oxford University Press 1992, p336

Andrew GO Lee, MD, Ashwini Kini, MD, Bayan Al Othman, MD. Ocular_Neuromyotonia, Amercian Academy of Ophthalmology, EyeWiki. April 7, 2023.

https://eyewiki.aao.org/Ocular_Neuromyotonia

Roper-Hall G, Chung SM, Cruz OA. Ocular neuromyotonia: differential diagnosis and treatment. Strabismus. 2013;21(2):131-136.

Eggenberger ER. Ocular neuromyotonia: report of 2 cases, review of the literature and pathophysiologic hypothesis. Neuro-Ophthalmology. 1999;21:249-254.

Stockman AC, Dieltiëns M, Janssens H, Van Lammeren M, Beelen L, Van Bellinghen V, Cassiman C. Ocular Neuromyotonia: Case Reports and Literature Review. Strabismus. 2018 Sep;26(3):133-141.

Chung SM, Lee AG, Holds JB, Roper-Hall G, Cruz OA. Ocular neuromyotonia in Graves dysthyroid orbitopathy. Arch Ophthalmol. 1997;115(3):365-70.

Menon D, Sreedharan SE, Gupta M, Nair MD. A novel association of ocular neuromyotonia with brainstem demyelination: two case reports. MultScler. 2014;20 (10):1409-1412.

Published

2023-09-26

How to Cite

[1]
Ebner, R. 2023. Ocular neuromyotonia post radiotherapy: case report. Oftalmología Clínica y Experimental. 16, 3 (Sep. 2023), e270-e274. DOI:https://doi.org/10.70313/2718.7446.v16.n03.244.

Issue

Section

Casos Clínicos

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