Chromatic pupillometry in primary open-angle glaucoma suspected patients
DOI:
https://doi.org/10.70313/2718.7446.v16.n04.258Keywords:
glaucoma suspect, chromatic pupillometry, flickering pupillary responsesAbstract
Purpose: The pupil light reflex to different colors lights (chromatic pupillometry) can be used as a biomarker of the retina functional state. In this work, we assessed the flickering pupillary response to colored stimuli in patients with suspected primary open-angle glaucoma.
Methods: 41 volunteers participated in this study: 20 glaucoma suspects and 21 healthy controls. A photostimulator-pupillometric system was used to record the flickering pupillary responses. Blue, green and red sinusoidal light stimuli (frequency = 1 Hz; duration = 10 secs) were used. Pupillary parameters in time and frequency domain were assessed for each group, and the differencies between them were analysed.
Results: Initial constriction, plateau, amplitude phase parameters were decreased in glaucoma suspected patients respect to the control group, for all stimuli conditions. However, time to minimum was constant between both groups.
Conclusions: The flickering pupillary responses were decreased in glaucoma suspected patients, suggesting a possible retinal cells disfunction. Early functional changes due to glaucoma could be assessed by flickering chromatic pupillometry.
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